6.2.1 Massively parallel signature sequencing (MPSS).6.1.1 Single molecule real time (SMRT) sequencing.
The rapid speed of sequencing attained with modern DNA sequencing technology has been instrumental in the sequencing of complete DNA sequences, or genomes, of numerous types and species of life, including the human genome and other complete DNA sequences of many animal, plant, and microbial species. Having a quick way to sequence DNA allows for faster and more individualized medical care to be administered, and for more organisms to be identified and cataloged. Comparing healthy and mutated DNA sequences can diagnose different diseases including various cancers, characterize antibody repertoire, and can be used to guide patient treatment. Knowledge of DNA sequences has become indispensable for basic biological research, and in numerous applied fields such as medical diagnosis, biotechnology, forensic biology, virology and biological systematics. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine.
DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA.
